Lymphocytes are the main cells that make up lymph tissue, a major part of the immune system.
Lymphocytes are mature WBCs that develop from lymphoblasts in the bone marrow. 
Macrophages also help lymphocytes recognize germs and make antibodies to fight them. After circulating in the bloodstream for about a day, monocytes enter body tissues to become macrophages, which can destroy some germs by surrounding and digesting them.
Monocytes are WBCs that develop from blood-forming monoblasts in the bone marrow. The 3 types of granulocytes – neutrophils, basophils, and eosinophils – are distinguished by the size and color of their granules. These granules contain enzymes and other substances that can destroy germs, such as bacteria. Granulocytes have granules that show up as spots under the microscope. Granulocytes are mature WBCs that develop from myeloblasts, a type of blood-forming cell in the bone marrow. White blood cells (WBCs) help the body fight infections. They help plug up holes in blood vessels caused by cuts or bruises. Platelets are important in stopping bleeding. Platelets are actually cell fragments made by a type of bone marrow cell called the megakaryocyte. Red blood cells (RBCs) carry oxygen from the lungs to all other tissues in the body, and take carbon dioxide back to the lungs to be removed. These myeloid cells are the ones that are abnormal in AML. Myeloid cells can develop into red blood cells, white blood cells (other than lymphocytes), or platelets. During this process, the cells become either lymphocytes (a kind of white blood cell) or other blood-forming cells, which are types of myeloid cells. Inside the bone marrow, blood stem cells develop into new blood cells. A small fraction of the blood-forming cells are blood stem cells. It is made up of blood-forming cells, fat cells, and supporting tissues. Bone marrowīone marrow is the soft inner part of certain bones. To understand leukemia, it helps to know about the blood and lymph systems. Normal bone marrow, blood, and lymph tissue The different types of AML are discussed in Acute Myeloid Leukemia (AML) Subtypes and Prognostic Factors.Īcute myeloid leukemia (AML) has many other names, including acute myelocytic leukemia, acute myelogenous leukemia, acute granulocytic leukemia, and acute non-lymphocytic leukemia. 
Most often, AML develops from cells that would turn into white blood cells (other than lymphocytes), but sometimes AML develops in other types of blood-forming cells. It can sometimes spread to other parts of the body including the lymph nodes, liver, spleen, central nervous system (brain and spinal cord), and testicles. There are several types of leukemia, which are divided based mainly on whether the leukemia is acute (fast growing) or chronic (slower growing), and whether it starts in myeloid cells or lymphoid cells.Īcute myeloid leukemia (AML) starts in the bone marrow (the soft inner part of certain bones, where new blood cells are made), but most often it quickly moves into the blood, as well. Most often, leukemia starts in early forms of white blood cells, but some leukemias start in other blood cell types. Leukemias are cancers that start in cells that would normally develop into different types of blood cells. To learn more about cancer and how it starts and grows, see What Is Cancer?
Cells in nearly any part of the body can become cancer. Cancer starts when cells in a part of the body begin to grow out of control.
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